Akt might be a target of ceramide, while inhibition of Akt by ceramide could lead to inhibition of the anti-apoptotic protein Bcl-XL by Bad (67, 68)

Akt might be a target of ceramide, while inhibition of Akt by ceramide could lead to inhibition of the anti-apoptotic protein Bcl-XL by Bad (67, 68). promote neuronal and cardiac cell death (5C7). This protein is definitely primarily a soluble protein in healthy cells (8C11). Upon treatment with a variety of apoptotic stimuli, Bax translocates… Continue reading Akt might be a target of ceramide, while inhibition of Akt by ceramide could lead to inhibition of the anti-apoptotic protein Bcl-XL by Bad (67, 68)